Built in 1887, the Argenta Drug Store is located in the Argenta Arts District and is the oldest continuously operating pharmacy west of the Mississippi River. It is housed in the oldest brick building in North Little Rock. Until 2006, a vintage classic Coca-Cola ad was painted on the 4th Street side of the building, but has since been restored.

When you step in to the drugstore, you step back in time. Little has changed since the 1950's, as it sports vintage apothecary wallpaper, the original pressed tin ceiling and hand-laid tile flooring.